Synonym word of hast had enough:

annoy, bore, burden, cause ennui, cloy, debilitate, depress, disgust, dishearten, distress, drain, droop, drowse, enervate, enfeeble, exasperate, exhaust, fade, fag, fail, fall off, fatigue, flag, glut, grow tired, harass, have had enough, irk, jade, leave one cold, lose i


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